从摄入到组织:磷脂消化、吸收代谢的脂质组学解析
从摄入到组织:磷脂消化、吸收代谢的脂质组学解析汇报人:杜润峰目录01磷脂的分类、来源与生理重要性02磷脂消化吸收的研究现状03LC-MRM-MS揭示不同PC消化、代谢物差异04不同PC对肝脏脂质代谢的影响磷脂的分类、来源与生理重要性PART0101.磷脂的分类、来源与生理重要性磷脂酰胆碱(PC)X为乙醇胺形成磷脂酰乙醇胺(PE)为丝氨酸形成磷脂酰丝氨酸(PS)为肌醇形成磷脂酰肌醇(PI)•C1和C2上的羟基被脂肪酸(R1、R2)所酯化,形成疏水性的非极性尾;•C3位上磷酸胆碱则构成亲水性的极性头,共同赋予了PC特有的双亲性,•双亲性使其能够在生物膜中自组装成脂双层,并参与多种生物学过程和生物学...
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